Duke Medical Center Library & Archives
CONSORT Statement Updated: new guidelines for reporting randomized controlled trials
Posted On: Tuesday, May 25, 2010 - 09:41 by Beverly Murphy
CONSORT 2010 Statement: updated guidelines for reporting parallel group randomised trials.Schulz KF, Altman DG, Moher D; CONSORT Group.
BMC Med. 2010 Mar 24; 8:18. PMID: 20334633
The CONSORT statement is used worldwide to improve the reporting of randomised controlled trials. Kenneth Schulz and colleagues describe the latest version, CONSORT 2010, which updates the reporting guideline based on new methodological evidence and accumulating experience.
To encourage dissemination of the CONSORT 2010 Statement, this article is freely accessible on bmj.com and will also be published in the Lancet, Obstetrics and...
Proton-Pump Inhibitors Increase Risks for C. Diff
Posted On: Tuesday, May 18, 2010 - 09:40 by Beverly Murphy
Proton-pump inhibitors (PPIs) are overprescribed, and as currently used, their harms mostly outweigh their benefits, researchers and an editorialist argue in the Archives of Internal Medicine. In one study, researchers analyzed data on more than 100,000 patients from a tertiary-care center to examine the association between intensity of acid-suppression therapy and incidence of nosocomial Clostridium difficile infection. They found that as suppression intensity increased, so did the odds ratio of infection: from 1.0 (no suppression), to 1.53 (with histamine-2–receptor antagonists), to 1.74 (with daily PPIs), to 2.36 (with more frequent PPIs).
Another study showed the effects of introducing guidelines on PPI use for preventing nosocomial upper GI bleeding. After implementation,...
Added Sugars May Affect Cholesterol
Posted On: Tuesday, May 11, 2010 - 12:10 by Adrianne Leonardelli
You may want to think twice before drinking that soda! A study, appearing recently in JAMA, concluded that people who consumed diets high in added sugars had lower HDL (good) cholesterol and higher triglyceride levels. When participants’ sugar intake was 25% or more of total consumed calories, HDL cholesterol was 47.7 mg/dL and triglyceride levels were 114 mg. In comparison, participants who consumed 5% or less of daily calories from sugar had higher levels of HDL cholesterol (58.7 mg/dL) and lower triglycerides (105 mg).
Read a more complete excerpt of this study.
Source: Welsh JA. Caloric sweetener consumption and dyslipidemia among US adults....
Crude Oil Spills and Human Health
Posted On: Thursday, April 29, 2010 - 12:08 by Beverly Murphy
A page of links to information on Crude Oil Spills and Human Health is now available from the National Library of Medicine.
The page provides links to information on how the United States responds to oil spills, state agencies in the Gulf region that respond to spills, occupational hazards for professionals and volunteers assisting with clean-up, seafood safety and more.
The links under "Featured Sites" focus on the latest updates about the recent spill and subsequent controlled burning of crude oil in the Gulf of Mexico. This spill followed the explosion and sinking of the Deepwater Horizon Mobile Offshore Drilling Unit oil platform 50 miles southeast of the Mississippi Delta on April 20, 2010.... MORE
Featured Resource: HealthPathNC
Posted On: Saturday, April 17, 2010 - 10:00 by Beverly Murphy
Public health–related documents are well represented within the State Library of North Carolina's digital collections. To provide a convenient access point to this information, and in preparation for future digitization efforts, they are introducing a new portal: HealthPathNC. Through this portal, you can access materials available in popular current collections like those on eugenics in North Carolina and the influenza epidemic of 1918– 1919. You can also more easily find groups of topically related public health documents. HealthPathNC includes multiple methods for accessing the public health collection, including keyword searching, browsing, and selecting from a variety of popular health topics. There is also a list of general resources... MORE
Proton-Pump Inhibitors and Clopidogrel: Important Interaction?
Posted On: Wednesday, April 14, 2010 - 08:53 by Beverly Murphy
Coronary heart disease patients who received both drugs experienced fewer hospitalizations for gastrointestinal bleeding than did those who received clopidogrel alone.
Researchers have suggested that concomitant use of clopidogrel and proton-pump inhibitors (PPIs) is associated with elevated risk for cardiovascular disease (CVD) events. In this retrospective cohort study, investigators reviewed Tennessee Medicaid data for 20,596 patients who received clopidogrel after hospitalization for myocardial infarctions (MIs), coronary artery revascularization, or unstable angina during a 7-year period; 37% received concomitant PPI therapy.
PPI recipients experienced fewer hospitalizations for gastrointestinal bleeding than did nonrecipients (8.2 vs. 12.2 per 1000 person-years... MORE
Cancer Surgery, Diabetes & Mortality
Posted On: Thursday, April 8, 2010 - 17:21 by Adrianne Leonardelli
In a systematic review and meta-analysis appearing in the April 2010 edition of Diabetes Care, researchers conclude that "cancer patients with preexisting diabetes are about 50% more likely to die after surgery than their nondiabetic counterparts".
The abstract of this article, Postoperative Mortality in Cancer Patients With Preexisting Diabetes, can be found online at: http://care.diabetesjournals.org/content/33/4/931
Health Care Reform News and Views
Posted On: Monday, April 5, 2010 - 12:29 by Beverly Murphy
The Washington Post has created a special section on the health care reform bill and associated news. View the full suite of stories and features online at http://voices.washingtonpost.com/health-care-reform/.
The Great Prostate Mistake
Posted On: Monday, March 15, 2010 - 08:14 by Beverly Murphy
The inventor of the PSA test for prostate cancer screening Prof Richard Ablin, in a very recent op-ed in the NY Times, today regrets his invention and rues how it has led to a multi-billion dollar profit driven public health disaster in the USA . He writes - I never dreamed that my discovery four decades ago would lead to such a profit-driven public health disaster. The medical community must confront reality and stop the inappropriate use of P.S.A. screening. Doing so would save billions of dollars and rescue millions of men from unnecessary, debilitating treatments.
You can read the entire editorial at the following Web-link:
The Wireless Future of Medicine
Posted On: Wednesday, March 10, 2010 - 09:43 by Beverly Murphy
Eric Topol: The Wireless Future of Medicine (17 min video)
Check out this TED talk on using mobile devices in health care. See some of the technology that can "take individualized medicine to a new height."
Eric Topol says we'll soon use our smartphones to monitor our vital signs and chronic conditions. At TEDMED, he highlights several of the most important wireless devices in medicine's future -- all helping to keep more of us out of hospital beds.
CDC Releases County-Level Atlas of Heart Disease Hospitalizations
Posted On: Friday, March 5, 2010 - 11:53 by Beverly Murphy
The CDC recently released the 2010 Atlas of Heart Disease Hospitalizations Among Medicare Beneficiaries, its first atlas showing hospitalization rates for heart disease at the county level. Heart disease is the leading cause of death in the US. These new maps chart wide disparities based on race/ethnicity and geographic location.
2010 Atlas of Heart Disease Hospitalizations Among Medicare Beneficiaries:
Interactive Heart Disease & Stroke Maps:
Online Encyclopedias Available
Posted On: Thursday, February 25, 2010 - 13:06 by Beverly Murphy
Starting a research project or paper and need some help identifying or learning more about a topic? Many health-related encyclopedias are available online, including:
- Encyclopedia of Obesity
- SAGE Handbook of Healthcare
- Encyclopedia of Stem Cell Research
- Encyclopedia of Epidemiology
- Encyclopedia of Global Health
CDC Releases 2009 U.S. Health Stats
Posted On: Monday, February 22, 2010 - 13:13 by Beverly Murphy
The CDC's National Center for Health Statistics has released its annual report, titled Health, United States, 2009. This year's edition contains a special focus on medical technology. The report is available for free online:
- The complete report (PDF; 574 pages)
- "In Brief" edition (PDF; 15 pages)
- The CDC's Health United States Website also contains special topics and downloadable presentations and charts.
A couple of findings from the data:
- The gap in life expectancy at birth between white persons and black persons persists but has narrowed since 1990.
Want to schedule a meeting the fast and easy way?
Posted On: Wednesday, February 17, 2010 - 12:59 by Beverly Murphy
Doodle takes the pain out of finding the right date and time for a group of people to meet and makes scheduling virtually effortless. The basic service is a free online coordination tool which requires neither registration nor software installation.
Doodle lets you create a poll with available dates and times for your meeting, allowing for different time zones. Doodle will then send you a web link to the schedule which you in turn email to your participants. They use the link to check their availability. The end result is an easy to view list of participants with their availability for the times listed in the poll.