Vivli: A Data Repository for Clinical Data

Now that the new NIH Data Management and Sharing Policy is in effect, researchers are taking a closer look at their options for where to deposit their data once the research project is complete. Indeed, the new policy requires researchers to prospectively plan for where they will share their data when they apply for NIH funding. If you work with human participant data and need a controlled access repository, Vivli may be a good option!

Vivli is a global clinical research data-sharing platform that focuses on sharing anonymized individual participant-level data. The platform includes a controlled access data repository, search engine, and secure research environment. As one of seven generalist repositories in the NIH Generalist Repository Ecosystem Initiative (or GREI), Vivli is part of the NIH data ecosystem. In addition, Duke University School of Medicine is an institutional member of Vivli, which means there is no cost for Duke researchers to deposit their data.

Vivli currently has over 7,000 clinical trials including 21 studies from Duke. You can share data from completed trials, including phase I-IV interventional studies, and observational studies in Vivli. Datasets are assigned a DOI so they will be findable and citable. Researchers interested in using data in Vivli must submit a research proposal to request the data. Once approved, they will sign a data use agreement and then be able to use the data, free of charge.

If you have specific questions about using Vivli as a data repository for Duke research, please contact  For more information on data repositories in general, please contact or